3Dneuro – Tools for brain & behavior neurocircuit research

Solutions for in vivo electrophysiology

In systems neuroscience, researchers often push the limits of experimental methods and equipment. We're here to help!

With a focus on brain implants in animal models, we help researchers who want to record neural activity to realize their new ideas faster and easier. To do that, we push the limits of 3D printing and machining to produce designs that combine performance, handling ease and user priorities such as enabling electrode reuse.

We also collaborate on multiple custom R&D projects, from rodent head fixation in VR setups and MRI scanners to various treadmill designs.

In line with our mission, we actively contribute to the open source/open hardware space.

See our X account @3Dneuro for company news and views.

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We specialize in making custom implants for in vivo (rodent) electrophysiology, to help researchers use cutting-edge high-density silicon probes, by themselves or together with other recording and stimulation tools.

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What our users say

3Dneuro drives are amazing, it now takes us mere minutes to recover previously implanted probes and shanks almost never break. It allows us to keep re-implanting the same probe until the recording sites wear off, it’s an absolute game changer and also a considerable money saver.

Model system Freely moving rats

Number of R2Drives per implant up to two

Duration of experiments Up to 1 week

Probe recovery success Pretty much 100% of the time

Read more:
Read more about Adrian's research and how he uses the R2Drive here.

Model system	Freely moving rats
Number of R2Drives per implant	up to two
Duration of experiments	Up to 1 week
Probe recovery success	Pretty much 100% of the time

Adrian J Duszkiewicz, PhD

Postdoctoral Fellow, Paul Dudchenko’s laboratory, University of Stirling

My first introduction to probe implants was using a drive that was completely incased in dental cement. The probe was not recoverable, and the drive was three times as expensive. R2Drives completely changed things for me. The R2Drives make probe implants and explants easy. I’m now able to reuse probes several times over, and the R2Drive remains reliable throughout reuse.

Model system Mouse - freely moving and headfixed. I have used rats in the past

Number of R2Drives per implant 1

Duration of experiments 2 – 6 months

Probe recovery success I have recovered 100% of my probes with the R2Drive, and reuse them at least 3 times (depending on the proportion of good channels).

Read more:
Read more about Laura's research and how she uses the R2Drive here.

Model system	Mouse - freely moving and headfixed. I have used rats in the past
Number of R2Drives per implant	1
Duration of experiments	2 – 6 months
Probe recovery success	I have recovered 100% of my probes with the R2Drive, and reuse them at least 3 times (depending on the proportion of good channels).

Laura Berkowitz, PhD

Postdoctoral Fellow, Schaffer-Nishimura lab, Cornell University

We utilize the R2Drives in pretty much every chronic implant that involves our silicon probes, it is extremely important for us to have a reliable and accurate way to implant our optoelectrodes. Recoverability is also a key feature that allows us to extend the life of a device over multiple implantations. Everyone who has worked with silicon probes knows how stressful it can be to handle them, having an easy-to-use platform is of great help. I always recommend them to our workshop participants.

Model system Rats and mice, freely moving and headfixed

Number of R2Drives per implant Usually just one, but we have plans of implanting up to 4 on a rat

Probe recovery success Every time, I haven’t had any issues with probe recovery.

Read more:
Read more about Roberto's research and how he uses the R2Drive here.

Model system	Rats and mice, freely moving and headfixed
Number of R2Drives per implant	Usually just one, but we have plans of implanting up to 4 on a rat
Probe recovery success	Every time, I haven’t had any issues with probe recovery.

Jose Roberto Lopez Ruiz, PhD

Research Investigator, Yoon Lab, University of Michigan

3Dneuro drives are amazing, it now takes us mere minutes to recover previously implanted probes and shanks almost never break. It allows us to keep re-implanting the same probe until the recording sites wear off, it’s an absolute game changer and also a considerable money saver.

Model system Freely moving rats

Number of R2Drives per implant up to two

Duration of experiments Up to 1 week

Probe recovery success Pretty much 100% of the time

Read more:
Read more about Adrian's research and how he uses the R2Drive here.

Model system	Freely moving rats
Number of R2Drives per implant	up to two
Duration of experiments	Up to 1 week
Probe recovery success	Pretty much 100% of the time

Adrian J Duszkiewicz, PhD

Postdoctoral Fellow, Paul Dudchenko’s laboratory, University of Stirling

My first introduction to probe implants was using a drive that was completely incased in dental cement. The probe was not recoverable, and the drive was three times as expensive. R2Drives completely changed things for me. The R2Drives make probe implants and explants easy. I’m now able to reuse probes several times over, and the R2Drive remains reliable throughout reuse.

Model system Mouse - freely moving and headfixed. I have used rats in the past

Number of R2Drives per implant 1

Duration of experiments 2 – 6 months

Probe recovery success I have recovered 100% of my probes with the R2Drive, and reuse them at least 3 times (depending on the proportion of good channels).

Read more:
Read more about Laura's research and how she uses the R2Drive here.

Model system	Mouse - freely moving and headfixed. I have used rats in the past
Number of R2Drives per implant	1
Duration of experiments	2 – 6 months
Probe recovery success	I have recovered 100% of my probes with the R2Drive, and reuse them at least 3 times (depending on the proportion of good channels).

Laura Berkowitz, PhD

Postdoctoral Fellow, Schaffer-Nishimura lab, Cornell University

We utilize the R2Drives in pretty much every chronic implant that involves our silicon probes, it is extremely important for us to have a reliable and accurate way to implant our optoelectrodes. Recoverability is also a key feature that allows us to extend the life of a device over multiple implantations. Everyone who has worked with silicon probes knows how stressful it can be to handle them, having an easy-to-use platform is of great help. I always recommend them to our workshop participants.

Model system Rats and mice, freely moving and headfixed

Number of R2Drives per implant Usually just one, but we have plans of implanting up to 4 on a rat

Probe recovery success Every time, I haven’t had any issues with probe recovery.

Read more:
Read more about Roberto's research and how he uses the R2Drive here.

Model system	Rats and mice, freely moving and headfixed
Number of R2Drives per implant	Usually just one, but we have plans of implanting up to 4 on a rat
Probe recovery success	Every time, I haven’t had any issues with probe recovery.

Jose Roberto Lopez Ruiz, PhD

Research Investigator, Yoon Lab, University of Michigan

3Dneuro drives are amazing, it now takes us mere minutes to recover previously implanted probes and shanks almost never break. It allows us to keep re-implanting the same probe until the recording sites wear off, it’s an absolute game changer and also a considerable money saver.

Model system Freely moving rats

Number of R2Drives per implant up to two

Duration of experiments Up to 1 week

Probe recovery success Pretty much 100% of the time

Read more:
Read more about Adrian's research and how he uses the R2Drive here.

Model system	Freely moving rats
Number of R2Drives per implant	up to two
Duration of experiments	Up to 1 week
Probe recovery success	Pretty much 100% of the time

Adrian J Duszkiewicz, PhD

Postdoctoral Fellow, Paul Dudchenko’s laboratory, University of Stirling

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Recent news

2025-04-03

Revising our pricing and growth strategy

As an open source company, we aim for a certain level of transparency. For example, our prices are publicly available. Today, we will also open up […]

2024-03-11

3Drive phased out

Our first microdrive was based on a single idea: Protect the silicon probe! To achieve that, we often flirted with the limits of 3D printing. The […]

2024-03-08

Methods preprints!

In the past month, two preprints featuring 3Dneuro were posted online and submitted for peer-review. This work is the result of longstanding collaborations with the Genzel […]

2022-06-15

Press: 3Dneuro featured in Dutch newsletter Bionieuws

Last month, Bionieuws – a professional newsletter for biologists – ran a feature on 3Dneuro (Letter 7, May 14 2022). Our co-founder Tim can be seen […]

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Have a question? Write to us!

Not sure what drive is right for you? Wondering whether you need a crown or not? Do you have questions about our ordering process or current lead times? Is there a problem in your setup that we can help with? Or do you want to give us feedback on drives you got from us? Then do not hesitate to get in touch either using the form below or messaging/@ing us on Twitter!